June 17-18

Times noted are US EST (US PST -3 hours, US CST -1 hours, Central Europe + 6 hours)

Day 1 (June 17), Morning session:

9: 45: Welcome (NTS President and Program Committee)

10: 00 -10:15 - MPTP intoxication in the Octodon degus: effects on the nigrostriatal pathway and related areas.

Lorena Cuenca-Bermejo (Mentor: Maria Trinidad Herrero)

10:15 - 10:30 - Early changes in epigenetics and oxidative stress in Old Parkinsonian mice.

Pablo Gallo-Soljancic. (Mentor: Maria Trinidad Herrero)

10:30 – 10:45 - Study of the anti-inflammatory and neuroprotective effect of flavonoid rutin in a pre-clinical model of Parkinson’s disease induced by aminochrome.

Fillipe Mendes De Araújo (Mentor: Victor Diogenes Amaral Silva)

10:45 – 11:30 - Discussion (Chair: María Trinidad Herrero)

11:30 - 11:45 - Break

11:45 – 12:00 - Cannabidiol attenuates non-motor symptoms in parkinsonian rats.

Bianca Andretto de Mattos (Mentor: Maria M. Weffort de Oliveira)

12:00 – 12:15 - Effects of ethyl-acetate fraction of Trichilia catigua on memory and oxidative stress after cerebral ischemia: An analysis of the time window of efficacy.

Daniela Velasquez de Oliveira (Mentor: Humberto Milani)

12:15 – 12:45 – Discussion (Chair: Harry Steinbusch)

End morning session

Day 1, afternoon session:

2:00 – 2: 15 -Different short-predictable stress in juvenile rats have no long-lasting effects on the volume of corpus callosum, hippocampus neither anxiety-like behavior or object recognition memory.

Lucas Brunati Gremaschi. (Mentor: Silvana Regina de Melo)

2:15 :2:30 - ALDH2 inhibition by Lead and Ethanol co-exposure: impact on bioenergetics and oxidative stress biomarkers in SH-SY5Y cells.

Romina Deza-Ponzio (Mentor: Miriam B. Virgolini)

2:30 – 2:45 - Changes of plasma PACAP-38 level in patients with Parkinson’s disease .

Daniel Pham (Mentor: Andrea Tamas)

2:45 – 3:00  - Modeling Parkinson´s Disease with AAV viral particles and human PFFs of α-Syn .

Mónica Gómez-Benito (Mentor: Rosario Moratalla)

3:00 - 4:15  - Discussion (Chair: Elaine del Bel)

End day 1

Day 2 (June 18):

10: 00 -10:15 - Increased expression of DSCAM and its action on neuronal morphological parameters in immortalized cell models of Down Syndrome. Possible role of the PAK effector pathway.

Ramón Pérez-Núñez (Mentor: Pablo Caviedes)

10:15 :10:30 - Evaluation of the impact of amyloid precursor protein (APP) and P21-activated kinase (PAK) on the morphological parameters in murine trisomy 16 neuronal cell lines, an animal model of Down syndrome.

Natalia Barraza (Mentor: Pablo Caviedes)

10:30 – 10:45 - Neuron glial antigen 2 in the striatum of parkinsonian rats presenting L-DOPA induced dyskinesia.

Nascimento G.C (Mentor: Elaine Del-Bel).

10:45 – 11:00 – LPS-Induced Inflammatory Reaction In Microglial Cells Is Prevented By Cannabidiol Through A Glucose Uptake-Dependent Oxidative Stress Mechanism.

Maurício Dos-Santos-Pereira (Mentor:  Elaine Del Bel)

11:00 - 11:45 – Discussion (Chair: Pablo Caviedes)

11:45 – 12:00 - Break

12:00 – 13:15 -  Open debate about neurotoxicity and current strategies